This refreshing cantaloupe smoothie recipe is lightly sweet and delicately fruity! All you need are 4 ingredients plus ice.

Cantaloupe smoothie

Got extra melon on hand? Try this refreshing Cantaloupe Smoothie! This one is lightly sweet and delicately fruity, balancing the melon with frozen pineapple and creamy Greek yogurt. We don’t always have this sweet fruit on hand, but when we do: this is how we use up leftovers! It’s bursting with flavor and takes just minutes to blend up. All you need are four ingredients, plus ice.

Ingredients in a cantaloupe smoothie

Melon is unique in smoothies because of the texture it produces: it becomes mostly liquid when blended. Instead of adding thickness to the smoothie texture like frozen berries or banana, melon becomes watery. So you’ll need to combine it with another fruit and ice to make a thick puree! Greek yogurt is also perfect for adding creaminess. Here’s what you’ll need for this cantaloupe smoothie:

  • Cantaloupe
  • Frozen pineapple
  • Greek yogurt
  • Orange juice
  • Ice
Cantaloupe smoothie

Why to add Greek yogurt

Greek yogurt is ideal for smoothies: it adds a creamy texture to the puree and a good dose of protein. You can use other types of yogurt if you don’t have it on hand: preferably plain yogurt without added sweeteners. However, this smoothie is only lightly sweet so it could handle a flavored yogurt if that’s all you have.

Want a vegan or dairy free cantaloupe smoothie? Just substitute oat milk, coconut milk or vegan yogurt for the Greek yogurt! Then consider one of the protein adders below.

Other protein adders

Want to add more protein to this cantaloupe smoothie? This is a good move if you’re planning to use it as a meal replacement, like for breakfast. Typically we recommend nut butter, but that would compete with the delicate melon flavor here. Here are a few options we’d try:

  • Chia seeds. Add protein and fiber with chia seeds! 2 tablespoons chia seeds adds 4 grams protein and 11 grams fiber. (See Chia Seed Smoothie.)
  • Vanilla protein powder: Protein powder also works here. Here’s the protein powder we like: it has a good flavor that’s not too artificial.
Cantaloupe smoothie

More fruit smoothies

Love the tropical flavor of melon in a smoothie, or prefer citrus or berry flavors? Here are a few more fruit smoothies to choose from:

This cantaloupe smoothie recipe is…

Vegetarian and gluten-free. For vegan, plant-based, and dairy-free, substitute oat milk or vegan yogurt.

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Cantaloupe smoothie

Cantaloupe Smoothie

  • Author: Sonja Overhiser
  • Prep Time: 5 minutes
  • Cook Time: 0 minutes
  • Total Time: 5 minutes
  • Yield: 2 small smoothies 1x


This refreshing cantaloupe smoothie recipe is lightly sweet and delicately fruity! All you need are 4 ingredients plus ice.


  • 3 cups cubed cantaloupe
  • 1 cup frozen pineapple
  • ½ cup Greek yogurt (or oat milk, coconut milk or vegan yogurt)
  • ½ cup ice
  • ½ cup orange juice


  1. Place the cantaloupe in a blender first and blend for a few seconds. Then add all other ingredients and blend until smooth, adding additional orange juice if necessary. Taste and if desired, add a bit of honey or pure maple syrup to sweeten. Serve immediately. Store up to 1 day refrigerated; it will separate so shake before serving.
  • Category: Drink
  • Method: Blended
  • Cuisine: Smoothie
  • Diet: Vegetarian

Keywords: Cantaloupe smoothie

About the authors

Sonja & Alex

Meet Sonja and Alex Overhiser: Husband and wife. Expert home cooks. Authors of recipes you'll want to make again and again.

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  1. I made the cantaloupe smoothie. I had home grown cantaloupe. I cut the recipe by 1/2 since I just wanted one serving. I used frozen pineapple, greek plain yogurt, and apple juice. Unfortunately my cantaloupe chunks were really big. Next time I’ll cut them up more. I didn’t need any ice. This was so refreshing, cooling and delicious!!! Thanks for the recipe. Next time I’ll add just a bit of honey or sugar. This time it was more like a sorbet! YUM.